CAG-encoded polyglutamine length polymorphism in the human genome
نویسندگان
چکیده
منابع مشابه
A linear lattice model for polyglutamine in CAG-expansion diseases.
Huntington's disease and several other neurological diseases are caused by expanded polyglutamine [poly(Gln)] tracts in different proteins. Mechanisms for expanded (>36 Gln residues) poly(Gln) toxicity include the formation of aggregates that recruit and sequester essential cellular proteins [Preisinger, E., Jordan, B. M., Kazantsev, A. & Housman, D. (1999) Phil. Trans. R. Soc. London B 354, 10...
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متن کاملCorrection: Pseudoautosomal Region 1 Length Polymorphism in the Human Population
Two errors are included in the published manuscript. In the abstract the sentence ‘‘Subsequent genomic analysis demonstrated that an insertional translocation of X chromosomal sequence into theMa Y chromosome generates an extended PAR.’’ Should read ‘‘Subsequent genomic analysis demonstrated that an insertional translocation of X chromosomal sequence into the Y chromosome generates an extended ...
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ژورنال
عنوان ژورنال: BMC Genomics
سال: 2007
ISSN: 1471-2164
DOI: 10.1186/1471-2164-8-126